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What are nootropics?

Nootropics are substances which enhance cognitive function and brain health in any number of ways. The best nootropics can improve everything from focus and learning to memory function and anxiety control. We recommend you use a comprehensive nootropic stack to help ensure that all aspects of brain function are addressed, including neuroplasticity, focus, learning, memory, energy, and brain cell health.

On this site you'll find dozens of in-depth nootropic stack reviews, nootropic compound and smart drug guides, and rankings of the best nootropics for a variety of purposes.

17 Best Nootropics For Energy: Boost Energy, Focus and Motivation

Published December 23, 2021 by Brian Johnson, PhD | Medically reviewed by Dr. DW Zaidel

Best nootropics for energy ranked

Tiredness, fatigue and braing fog are disastrous for productivity. We’ve all been there. You’ve had 5 hours of sleep, your morning has been mentally taxing, and you have hours of meetings ahead of you in the afternoon. By about 3pm, your mental performance is likely to be abysmal: your short-term memory will be impaired, your […]

Filed Under: Nootropics, Energy

Best Nootropics For Depression: Brain Supplements to Improve Mood and Fight Anxiety

Published December 21, 2021 by Brian Johnson, PhD | Medically reviewed by Dr. DW Zaidel

Best nootropics for depression

Using nootropics to treat depression is a controversial topic in the psychiatric world. Depression is often spoken about as a disease for which there is no real treatment. To read depression forums and blogs, you would get the impression that mood disorders were all caused by neurochemical imbalances that can always be treated with pharmaceutical […]

Filed Under: Nootropics

Alpha Brain vs Adderall: Which is a better nootropic?

Published December 20, 2021 by Brian Johnson, PhD | Medically reviewed by Dr. DW Zaidel

Alpha Brain vs Adderall

One of the most frequent questions we see asked in nootropics forums and on nootropics review sites is how pre-made nootropic stacks like Alpha Brain compare to synthetic smart drugs and pharmaceuticals like Adderall. Some people have suggested that Alpha Brain can act as a great over-the-counter alternative to Adderall. Others have published very negative […]

Filed Under: Nootropics

Alpha Brain Side Effects: Does it make you SICK?

Published December 20, 2021 by Brian Johnson, PhD | Medically reviewed by Dr. DW Zaidel

Negative side effects of Alpha Brain

Alpha Brain is, hands down, one of the most popular nootropics on the market. Alpha Brain was Onnit’s first product to come to market, and despite them branching out into a wide range of supplements, it remains their best-selling and best-known product. While it is rarely listed among the best nootropics anymore, Onnit Alpha Brain […]

Filed Under: Nootropics

N-Acetyl-L-Tyrosine vs L-Tyrosine: Which is better?

Published December 20, 2021 by Brian Johnson, PhD | Medically reviewed by Dr. DW Zaidel

L-Tyrosine vs N-Acetyl-L-Tyrosine NALT

Tyrosine is one of the best nootropics in existence. It is one of the most effective nootropics for boosting motivation, and it has broad beneficial effects on cognitive function as well. This is why almost all high-quality nootropic stacks contain some Tyrosine. There are multiple different forms of Tyrosine to take. As a naturally occurring […]

Filed Under: Nootropics

L-Theanine Tyrosine Stack: Should you take them together?

Published December 20, 2021 by Brian Johnson, PhD | Medically reviewed by Dr. DW Zaidel

Theanine Tyrosine stack

L-Theanine and L-Tyrosine are two amino acids routinely used in pre-made nootropic stacks. There’s good reason for this; both of these natural nootropic ingredients really work to improve mental performance. All of our top rated nootropics contain both Theanine and Tyrosine in some form or another. One question we get asked quite frequently is whether […]

Filed Under: Nootropics, Energy

CDP-Choline vs Alpha-GPC: Is Citicoline better than Alpha-GPC? What’s the difference?

Published November 23, 2021 by Brian Johnson, PhD | Medically reviewed by Dr. DW Zaidel

Alpha-GPC vs Citicoline

CDP-Choline (aka Citicoline) and Alpha-GPC are two of the most popular choline supplements on the market today. Alpha-GPC and Citicoline have different benefits and effects in the brain. Alpha-GPC works faster than CDP-Choline in some studies, while CDP-Choline is likely more effective for enhancing focus, learning and mental energy. Citicoline may also protect the brain […]

Filed Under: Nootropics, Citicoline

Alpha-GPC vs Choline Bitartrate: What is the difference? Which is better?

Published October 15, 2021 by Brian Johnson, PhD | Medically reviewed by Dr. DW Zaidel

Best choline supplement to take

Two of the most widely-used cholinergics in the nootropics world are Alpha-GPC and Choline Bitartrate. These two brain supplements, along with Citicoline, are the most effective natural cholinergics you can purchase over the counter today. For those of you that don’t know, a cholinergic is a source of choline which, when taken as a supplement, […]

Filed Under: Nootropics

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    See our top rated nootropics right now

    Best nootropics

    Top Rated Nootropics

    • Nooceptin
      Nooceptin
      4.95
    • Vyvamind
      Vyvamind
      4.75
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      NooCube
      4.7
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      Mind Lab Pro
      4.3
    • Genius Consciousness
      Genius Consciousness
      3.55

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