9-Me-BC is one of those compounds that we have delayed reviewing for no good reason. It is probably one of the more popular of the nootropic research chemicals commonly used by biohackers and nootropics enthusiasts today. There has been a lot of discussion about 9-Me-BC on nootropics forums (mostly Reddit) in the last few months, so we thought it was time we did a proper analysis of the compound so you know everything you need to know before you consider using it.
Is 9-Me-BC a top nootropic? Is it a good choice for a daily cognitive enhancer? Is 9-Me-BC safe? What are the side effects like? Can you even buy it legally over the counter?
In this article, we’re going to answer all of these questions and more. We will look at what 9-Me-BC is, how it works, its side effects, and where you can buy it online. If you have personal experiences with this compound, please let us know in the comments how it worked for you.
What is 9-MeBC?
The compound 9-MeBC has potent cognitive-enhancing properties. It is part of a group of drugs known as dopaminergic, which are drugs that increase dopamine activity in the brain. An increase in dopamine activity or levels can translate into increased alertness, mood improvement, and spatial learning. These properties are why some people consider using it to enhance their cognitive abilities.
This substance isn’t well-known by most “smart drugs” users because it isn’t mainstream. It is thought to function in a similar way to other mainstream nootropics like modafinil and armodafinil. It regulates brain levels of serotonin and dopamine (GABA), according to researchers. These chemicals have been shown to affect alertness, mood, wake-sleep cycles, and alertness.
9-MeBC is a new nootropic. Studies are currently being done to find out more about its safety and benefits. It is being investigated as a potential treatment for Parkinson’s Disease.
9-MeBC Active Compounds
9-MeBC’s main ingredient is beta-carboline (b–carboline). It is a member of a group of carbolines found naturally in the brain, blood, meats, fruits and coffee.
B-carboline is well known for its antioxidant properties and ability to affect brain function.
How Does 9-Me-BC Work?
A 2012 rodent study revealed that the nootropic stimulates neuron growth and increases dopamine levels in brains. After about 10 days, the drug’s effects were evident in the study. The rats showed improved visuo-spatial performance and better memory function.
Dopamine, one of the most important neurotransmitters in the brain, is partly or entirely responsible for alertness, motivation, memory retention, learning, and mood, among many other cognitive functions. 9-Me-BC can slow down the reabsorption of dopamine by your neurons, increasing the total amount of dopamine available in the brain, thereby boosting focus, motivation, mood and learning ability.
It is important to note that there are still no extensive human trials on 9-Me-BC and no conclusive evidence of its safety or effectiveness in humans. Before you take the drug, consult your doctor.
Does 9-me-bc boost dopamine?
9-me-bc acts as a dopamine reuptake inhibitor. This means it slows or completely prevents the reabsorption of dopamine by your synapses after the neurotransmitter has transmitted its “message”. This means there is more dopamine activating neuronal receptors for longer. In practical terms, the results of this are increased motivation, greater mental clarity, and improved mood.
Benefits of 9 Me-BC
9-MeBC offers a variety of benefits. Some of these include:
Individuals who take 9-MeBC experience increased wakefulness. This is a common feature of nootropics and 9-Me-BC is no exception. It may be helpful for people who have excessive daytime sleepiness and want to remain awake throughout the day.
9-MeBC improves alertness by increasing brain dopamine levels. The brain’s dopamine levels at any given time are linked to alertness, mood, wake-sleep cycles, and alertness.
It improves your mood
Dopamine levels can influence mood, as we have already mentioned. People who have tried this nootropic say they feel more productive and alert after using it.
Improves memory function
The trials in rats showed that 9-MeBC improves spatial learning. The compound was administered to Thar rats for 10 days. They completed mazes faster than normal. This shows the effect of the drug on their learning capacity.
Dopamine levels high in dopamine can promote happiness, pleasure and satisfaction. People who take 9-MeBC may feel more motivated to work.
It is important to note that 9-MeBC’s benefits are not supported by any substantial research. They are merely anecdotal. Before you start treatment with this drug, consult your doctor.
Can 9-Me-BC help with Parkinson’s?
There has been some recent clinical research on 9-me-bc as a potential treatment or combination therapy for Parkinson’s Disease. Knowing that 9-me-bc likely acts as a dopamine reuptake inhibitor, this makes sense; many accepted treatments for Parkinson’s disease work by raising dopamine levels throughout the brain or in parts most associated with the condition.
Interestingly, in one study, researchers noted several different ways in which 9-me-bc may help with the progression of Parkinson’s disease:
Tyrosine hydroxylase (TH) expression was stimulated in pre-existing dopa decarboxylase immunoreactive neurons and several TH-relevant transcription factors (Gata2, Gata3, Creb1, Crebbp) were up-regulated. Neurite outgrowth of TH immunoreactive (THir) neurons was likewise stimulated. The interaction with tyrosine kinases (protein kinase A and C, epidermal growth factor-receptor, fibroblast growth factor-receptor and neural cell adhesion molecule) turned out to be decisive for these observed effects. Second, 9-me-BC protected in acute toxicity models THir neurons against lipopolysaccharide and 2,9-dime-BC(+) toxicity. Third, in a chronic toxicity model when cells were treated with 9-me-BC after chronic rotenone administration, a pronounced regeneration of THir neurons was observed. Fourth, 9-me-BC inhibited the proliferation of microglia induced by toxin treatment and installed an anti-inflammatory environment by decreasing the expression of inflammatory cytokines and receptors. Finally, 9-me-BC lowered the content of alpha-synuclein protein in the cultures. (source)
Obviously, more work is needed before anyone concludes that 9-me-bc can help with Parkinson’s.
Dosage Guide for 9-MeBC
Properly taking drugs is essential for their effectiveness without side effects. At the time of writing, however, there was no established dosage guide. Users recommend that you take 1 capsule daily with plenty of water. Side effects may be more likely if you take more capsules. The powdered version of the drug has not yet been prescribed.
To avoid severe side effects, do not take this medication without first consulting your doctor.
Warnings and Side Effects
Side effects are a part of all drugs, including 9-MeBC. It is still quite new in the nootropic world and is under-researched so there is not much information on its potential negative side effects. These are some of the side effects associated with smart drugs. There is a chance that 9-MeBC could have similar effects. These include:
- An upset stomach
Side effects that can be more serious include depression, hallucinations and rashes. This is often due to incorrect use of the drug.
9-me-bc DNA damage?
Does 9-me-bc cause DNA damage?
This is, unfortunately, a real possibility. β-carboline alkaloids are very efficient photosynthesizers, and 9-me-bc is particularly efficient compared to other β-carboline alkaloids. This means that these compounds may cause DNA damage in cells when exposed to UVA radiation, which is the majority of the radiation in sunlight.
We strongly recommend staying out of the sun as much as possible if you are going to use 9-me-bc.
Where can you buy 9-MeBC online?
9-MeBC can be purchased online by many online drug sellers. This is good news but it is important to be aware of the risks. Fake sellers sell counterfeit medications. The only way to ensure you get high-quality medication is to order them from trusted online pharmacies.
At this moment, there is no 9-Me BC vendor. ViaBestBuys.com or CialisBit.com can be trusted vendors to source modafinil and armodafinil if you are looking for safer and more effective options.
The Verdict: Complete 9-MeBC Review
9-MeBC is a cognitive-enhancing drug that may be effective at improving a range of cognitive functions and measures of brain health. However, it is not recommended to purchase and use as it is still understudied, at least when compared to the likes of Modafinil and Fasoracetam.
If you are looking for a compound to help you be more productive, mentally sharper and a more efficient learner, then we strongly recommend using a comprehensive nootropic stack.
A natural nootropic stack is much better suited to long-term daily use than research chemicals like 9-me-bc and they can be just as effective, if not more so!
Brian Johnson is current Editor of Vagarights.com and a long-time writer for VAGA. A former psychologist, Brian is passionate about improving mental health and finding ways to stave off cognitive decline. He is an expert on nootropics, cognitive enhancement and biohacking more broadly. You can see his work on Google scholar.